Bacteria as a Vast Unexplored Medicine Chest

first_img(Visited 10 times, 1 visits today)FacebookTwitterPinterestSave分享0 Most of our therapeutic agents have been derived from bacteria.  A new survey shows we have barely tapped the surface of potential medicines beneath our feet.Science Daily reported on a study of three desert soils from California, Arizona and Utah published in the May issue of Applied and Environmental Microbiology.  A team from Howard Hughes Medical Institute found “greater diversity of potentially useful products than was previously supposed” in the biosynthetic genes of soil bacteria, implying that “environmental bacteria have the potential to encode a large additional treasure trove of new medicines.”  The article explained where most of our medicines come from:Natural compounds have been the sources of the majority of new drugs approved by the US Food and Drug Administration, and bacteria have been the biggest single source of these therapeutically relevant compounds. Most bacterially-derived antibiotic and anticancer agents were discovered by culturing bacteria from environmental samples, and then examining the metabolites they produce in laboratory fermentation studies. But the vast majority of bacterial species cannot be cultured, which suggested that the world might be awash in potentially useful, but unknown bacterial metabolites.It seems that researchers will not soon run out of material to investigate: “the genomes of environmental bacteria could encode many additional drug-like molecules, including compounds that might serve, among other things, as new antibiotics and anticancer agents.”When you think of bacteria, do you think of health?  Maybe findings like this will help end a kind of microbial racism.  A few bad ones should not create bias against the majority that work hard to create a better world.This survey also suggests that bacteria originally had a useful function in the Creation paradigm.last_img read more

Rio Olympics: Indian men’s hockey squad likely to be named on July 5

first_imgHockey India (HI) selectors are likely to announce the men’s squad for the Rio Olympics on July 5 while the two-week national camp will start on July 11, chief coach Roelant Oltmans said on Friday.The team, captained by star goalkeeper P.R. Sreejesh, is currently preparing for the Champions Trophy in London from June 10 before heading off to Valencia, Spain, to play the six nations invitational tournament. The team will return to India in the first week of July.PRACTICE TO TAKE PLACE IN MADRIDAs part of the final preparations for the Rio Games, the team will leave for Madrid to play two friendly matches with Spain and then head to Rio for a friendly with Spain and New Zealand before participating in the quadrennial event.”The national selectors are likely to meet on July 5 to pick the final squad for the Olympics,” Oltmans said in a release.NATIONAL CAMP ON JULY 11″We will start the national camp on July 11 which will be a two-week camp after we leave for Madrid, to play two friendly matches with Spain and then head to Rio and have a friendly with Spain and New Zealand,” he added.”I believe we have entered a very exciting period in the lead up to the Olympics.”Ahead of the hectic schedule, the 29-member Champions Trophy-bound team has been allowed to take a week’s break before rejoining on May 29.”Starting June 5, the team will be away for almost a month playing two different tournaments in two different countries. Everything we do in this period will be demanding not just physically but also mentally,” the high performance director for Hockey India said.advertisement”Though we are entering an exciting period and looking forward to the Olympics, vying to peak at Rio, it was important to take off for a week and be in a different environment.”PLAYERS ASKED TO STICK TO STRICT DIETDespite the break, the Dutchman has suggested to the players to stick to a healthy diet and a specific programme to follow.”This includes gym and running only to ensure they stay at the same fitness level,” Oltmans said.While Oltmans will get to celebrate his 62nd birthday with his wife and three sons, Sreejesh is eager to meet his two-year-daughter back in Kerala.”Last night over the phone she was asking when is daddy coming home. We have been away training really hard the past six weeks and this break with family will only help us come back feeling fresh and eager to win,” said Sreejesh.last_img read more